One Step Closer to Understanding Fish Health in Potomac and Shenandoah Rivers
Released: 6/3/2009 11:03:39 AM
Estrogen Linked to Lowered Immunity in Fish
Exposure to estrogen reduces production of
immune-related proteins in fish. This suggests that certain compounds,
known as endocrine disruptors, may make fish more susceptible to
disease.
The research may provide new clues for why intersex fish, fish kills
and fish lesions often occur together in the Shenandoah and Potomac
rivers. The tests were conducted in a lab by scientists from the U.S.
Geological Survey.
The study, led by USGS genomics researcher Dr. Laura Robertson,
revealed that largemouth bass injected with estrogen produced lowered
levels of hepcidin, an important iron-regulating hormone in mammals
that is also found in fish and amphibians. This is the first published
study demonstrating control of hepcidin by estrogen in any animal.